Parathyroid Hormone in Pregnancy: Vitamin D and Other Determinants

نویسندگان

چکیده

We aimed to assess the parathyroid hormone (PTH) concentration in pregnant women at beginning of pregnancy (1st trimester) and within days before delivery (3rd evaluate its determinants. From September 2014 through December 2015 a cross-sectional study, 204 1st trimester 203 3rd were recruited. Blood samples collected measure PTH circulating 25-hydroxy-vitamin D (25(OH)D) concentrations. Lifestyle demographic data using questionnaire. Serum 25(OH)D inversely correlated both early late pregnancy. Our analyses suggest that pregnancy, level 18.9 ng/mL (47.3 nmol/L) could serve as an inflection point for maximal suppression PTH. Statistically significant determinants concentrations multiple regression concentrations, season, multiparity education partner (all p < 0.05) In country origin statistically 0.05). These factors their effect on appear be vastly determined by 25(OH)D; however, they might also affect other mechanisms besides 25(OH)D.

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ژورنال

عنوان ژورنال: Nutrients

سال: 2021

ISSN: ['2072-6643']

DOI: https://doi.org/10.3390/nu13020360